East Shore District Health Department
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Naloxone, also known as Narcan, is a medication that reverses opioid overdoses. It is a safe and easy to use medication that you can get over-the-counter at most pharmacies.
How does naloxone work?
When a person takes an opioid, it enters the brain and attaches to “opioid receptors” that give the user a “hit” or a “high”. The Naloxone goes to those same opioid receptors, removes the drug, and binds to the receptors to block the effects from the opioid. It is fast acting but is also short acting; meaning it does the job quickly but may not last longer than the opioids that are still in the body. After about 30 to 90 minutes the naloxone will wear off. It is possible that the person may go into an overdose situation again; therefore, it is important to call 911 any time you give naloxone.
Minutes count in an opioid overdose. If you think someone has overdosed, follow these steps:
Tell the dispatcher where you are and that someone is not breathing or is unconscious.
Don’t be afraid to call 911 for help!
If you can’t stay until 911 help arrives, place the person on their side, and where first responders can find them.
Naloxone can take 2-3 minutes to work. If the person is not breathing start giving rescue breaths.
If the person is still not breathing after 2-3 minutes, give a second dose of naloxone.
